ABSTRACT
A Novel corona virus (covid -19) was identified in 2019 in Wuhan, China. Greater proportion of patients infected by covid 19 may show signs of kidney damage. hyperuricemia has attracted greater attention. However, limited concern has been paid to the potential dangers of lowering serum uric acid. MATERIAL: this was a retrospective observational study based on 150 cases with covid 19 infection. we compared serum uric acid among two Group A - Saturation Above 90% and Group B Saturation Below 90%. Serum uric acid levels were divided into three ranges <3.5mg/dl, 3.5 to 4.5 mg/ dl and >4.5mg/dl and compared between the two groups. OBSERVATION: the age group of patients was in the range of 18years to 70 years with maximum number of patients in between the age group of 30-50 years. females constituted 32% (24), males 68% (51) belonging to group A and females 28% (21), males 72% (54) in group B. Blood urea nitrogen levels was highest in group A 77.3% (58) and the level is <40mg/dl. Serum Uric acid level <3.5 had 22.7% (17) than compared to group A having 18.7% (14). Serum uric acid level of 3.5 - 4.5 mg/dl had maximum number of patients from group B 22.7% (17) than compared to group A 16% (12). Maximum number of patients 50.7% (38) in group B had serum uric acid more than 4.5mg/dl than compared to group A 14.7% (11) accounting to a total of 33.3% (50) of the total patients. CONCLUSION: according to the observations from the data collected we can suggest that there is a possible relationship between the serum uric acid and covid severity. This retrospective study determined that the higher levels of serum uric acid levels in the critical group was higher than compared to severe group and it can be used a prognostic factor to asses the severity of outcome of covid 19 infection. this retrospective study suggested that uric acid, a purine base metabolite can be used a prognostic indicator in critically ill covid 19 patients. in the future, whether uric acid can be used to accurately reflect the viral load needs to be investigated.